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Table 1

Ranking of probe clusters within the consensus sites for thermolysin1

Consensus Site2
Probe
Isopropanol
Phenol
Acetone
Acetonitrile
1 (S1')
2 (0.69)
2 (0.69)
4 (0.75)
3 (0.32)
2 (S1)
-
1 (3.52)
2 (3.74)
1 (3.88)
3
-
4 (17.28)
1 (18.10)
2 (17.42)

1 - The distance of each cluster center from the isopropanol position (IPA 1 in ref. 8) is shown in parentheses.

2 - The two consensus sites in the substrate binding region are shown in bold.