Dr. Melissa Landon

Dr. Melissa Landon

My research focuses on studies of chemical diversity and protein-small molecule interactions for applications in rational drug design. One of my projects involves collaboration with the Center for Chemical Methodology and Library Development (CMLD) at BU on the development of new computational methodologies for assessing the structural diversity of chemical libraries. My work in the Vajda laboratory is currently focused on the extension of computational solvent mapping to allow for the mapping of hundreds of drug-like fragments on therapeutic targets. I'm also very interested in enzymology studies as they relate to protein-ligand interactions and plan on using PRECISE to investigate the relationships between the chemical space of small molecules and the structural space of proteins.