Dr. Stefan Jehle

Dr. Stefan Jehle

My scientific interests focus on the structure and function of biomolecular complexes, especially protein-protein interactions, and the design of small molecules to modulate their function.

During my career, I have gained experience in the application of Nuclear Magnetic Resonance (NMR) spectroscopy, SAXS and biochemical techniques for the characterization of the structure and function of proteins, protein-protein, protein-ligand, and protein-RNA complexes with an emphasis on the study of targets tightly connected to human disease.

In my role at Boston University I am using various biophysical techniques including X-ray crystallography for rational and fragment based lead discovery for protein-protein interactions.