Papers+Conferences

2018
Beglov D, Hall DR, Wakefield AE, Luo L, Allen KN, Kozakov D, Whitty A, Vajda S.  2018.  Exploring the structural origins of cryptic sites on proteins. Proceedings of the National Academy of Sciences. 5428138365835429Chap 2:201711490.
2016
2015
Vajda S, Whitty A, Kozakov D.  2015.  Fragments and hot spots in drug discovery. Oncotarget. 6(22):18740-18741. Download: PDF (504.45 KB)
Hall DR, Kozakov D, Whitty A, Vajda S.  2015.  Lessons from Hot Spot Analysis for Fragment-Based Drug Discovery.. Trends in Pharmacological Sciences. 36(11):724-36. Download: PDF (2.27 MB)
Kozakov D, Hall DR, Napoleon RL, Yueh C, Whitty A, Vajda S.  2015.  New Frontiers in Druggability. Journal of Medicinal Chemistry. :150811124427009. Download: PDF (9.06 MB)
Kozakov D, Hall DR, Jehle S, Luo L, Ochiana SO, Jones EV, Pollastri M, Allen KN, Whitty A, Vajda S.  2015.  Ligand deconstruction: Why some fragment binding positions are conserved and others are not. Proceedings of the National Academy of Sciences. :201501567. Download: PDF (1003.22 KB)
2014
Villar EA, Beglov D, Chennamadhavuni S, Porco JA, Kozakov D, Vajda S, Whitty A.  2014.  How proteins bind macrocycles. Nature Chemical Biology.  Download: PDF (1.17 MB)
2013